Cell-Cell Signaling Through NOTCH Regulates Human Embryonic Stem Cell Proliferation
نویسندگان
چکیده
منابع مشابه
Hes1 regulates embryonic stem cell differentiation by suppressing Notch signaling
Embryonic stem (ES) cells display heterogeneous responses upon induction of differentiation. Recent analysis has shown that Hes1 expression oscillates with a period of about 3-5 h in mouse ES cells and that this oscillating expression contributes to the heterogeneous responses: Hes1-high ES cells are prone to the mesodermal fate, while Hes1-low ES cells are prone to the neural fate. These outco...
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ژورنال
عنوان ژورنال: Stem Cells
سال: 2008
ISSN: 1066-5099,1549-4918
DOI: 10.1634/stemcells.2007-0368